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EMM Sequence Analysis (EMMSA)

 

The Extensible Markov Model (EMM) is a spatiotemporal modeling tool that has been successfully applied to many domains and applications (flood prediction, anomaly detection in VoIP traffic,  anomaly detection to automobile traffic, intrusion detection, miRNA prediction).  The objective of the EMMSA project is the creation of an online tool to facilitate the use of EMM in analyzing DNA/RNA sequences.  Without first performing an expensive alignment effort, an EMM models the sequence of subpatterns (of any length) within a longer nucleotide sequence.  By creating EMMs to model the normal behavior of a class of sequences, new unknown sequences can be evaluated as to membership in this class using a metaclassification approach, MCM.